AerovectRx Names Tom Callaway as CEO

June 2, 2009 (Atlanta, GA) Thomas H. Callaway, M.D., MBA, has been named Chief Executive Officer of AerovectRx Corporation, an Atlanta-based inhaled, aerosol drug-delivery company.

Prior to joining AerovectRx, Tom was founder and President of Life Science Partner, an executive search firm focused on recruiting scientific and managerial leaders for the life sciences industry. He was also a founding partner of Georgia Venture Partners, established in 2004 to make seed and early-stage investments in life sciences enterprises related to Georgia. He is a former partner with Fuqua Ventures (a life science and technology venture capital fund) and two leading recruiting firms Russell Reynolds and Korn/Ferry International.

Before moving to Atlanta, Dr. Callaway held the position of Director, Commercial Development for SyStemix, responsible for business development and marketing for the firm’s proprietary stem cell technology. He began his biotechnology career at Roche Diagnostics and Roche Molecular Systems. During his tenure at Roche, he developed and executed a global marketing plan for polymerase chain reaction (PCR) diagnostics technology, a Noble-prize winning solution for sleuthing out specific sequences of DNA and commercializing the tools to map the human genome.

“With the appointment of Tom as CEO, AerovectRx has secured a successful, experienced and highly capable executive,” said P. Kathleen Lovell, Board Chairman.

Dr. Callaway added, “Inhaled drug delivery is emerging as one of the most lucrative segments in the pharma industry and I am very excited to become a part of the AerovectRx team as we accelerate into this opportunity.”

Dr. Callaway earned a medical degree from Vanderbilt University School of Medicine. He holds an MBA and undergraduate degree from Duke University.

Dr. Callaway was recently awarded the 2009 Georgia Bio Industry Growth Award as recognition for his years of service and extraordinary contributions to Georgia’s life sciences community and as a mentor to industry entrepreneurs.

Tom is an active member of the Southeast investment community, serving on the board of Atlanta Venture Forum, Southeast Bio, and the Bio 2009 Executive Committee. He is a member of the corporate board of Aruna Biomedical, Aterain, and Neurop.

Callaway, 49, has served since December 2008 as AerovectRx interim CEO.

More About AerovectRx

Callaway: In biotech, GA is a PC

May 21, 2009 (Atlanta, GA) Thomas H. Callaway, M.D., MBA, has been named Chief Executive Officer of AerovectRx Corporation, an Atlanta-based inhaled, aerosol drug-delivery company.

When it comes to biotech, North Carolina and Florida are like the Mac, while Georgia is the PC, said Tom Callaway, referring to the “Get a Mac” television commercials..

"We're a little bit bolted together," quipped Callaway, managing director at Georgia Venture Partners LLC. “We have some private groups that are very interesting, that are innovative, and work. Yet, we don’t quite have it exactly smoothly put together, with the level of support that [North Carolina and Florida] have.” Callaway.

Callaway was speaking at the tail-end of the four day 2009 BIO International Convention. The discussion, Financing the Southeast Biotech Sector, included regional venture capitalists..

North Carolina gradually developed its biotech creds by attracting pharmaceutical giants like Glaxo, Callaway said.

Florida, meanwhile, used the “add water and stir” approach. The state gained instant biotech cred by recruiting The Scripps Research Institute to open a biomedical research facility in Jupiter, Fla., Callaway said.

While Georgia might need work on its coordination, the state has the parts to develop a strong biotech industry. .

Georgia has a "lot of the tools" in basic science and a strong research foundation thanks to Emory University, Georgia State and The University of Georgia, Callaway said.

He referred to Georgia Tech as “probably No. 2 to MIT.”

The Peach State also has an "incredible logistics information backbone" and a strong entrepreneurial culture, Callaway noted.

“We are the place where Ted Turner created his great empire,” he said.

Metro Atlanta has groomed several entrepreneurs in the Internet sector, who have provided mentorship for other technology companies, Callaway said.

“Unfortunately, we have yet to build that same level of expertise within the lifesciences,” he said. “We are working on it.”

The Georgia legislature's short-term focus, however, has hurt the lifesciences business, Callaway said.

Unlike the North Carolina government, which invested in biotech for 25 years, Callaway said, "we tend to focus [on the short term] and say what's our return?"

Read AtlanTech Blog Article

Visioneering Technologies Inc. Raises $5 Million in Funding for New Presbyopia Solution

April 27, 2009 (Atlanta, GA) Visioneering Technologies Inc. (VTI), a startup company with what it describes as breakthrough technology for correcting presbyopia through contact lenses and other on eye/in eye applications, announced the closing of its Series B round of financing led by MB Ventures of Memphis, Tenn.

The company, which has raised nearly $5 million to date, has added investment partners to fund completion of its clinical trials. Other major investors include Charter Life Sciences and Life Science Angels, both of Palo Alto, Calif., and the State of Georgia through its ATDC Seed Capital Fund.

VTI’s patented approach to vision correction utilizes induced aperture optics to improve the optical efficiency of the eye’s vision system. The technology has a number of on eye and in eye applications including contact lenses, LASIK, intraocular lenses and corneal inlays.

According to industry veteran Joe DeLapp, VTI’s president and CEO, “VTI’s initial play into the marketplace will be the contact lens category, where solutions for presbyopia correction have fallen short of consumer expectations. With the aging demographics of the population, VTI’s solution for presbyopia provides an enormous market opportunity.”

Visioneering Technologies Inc. was founded in 2004 by Dr. Richard A. Griffin, an optometrist, optical engineer and aerospace engineer who spent 20 years developing VTI’s breakthrough technology. Griffin holds two issued patents for his unique optical solutions for presbyopia.

Read the VisionMonday Article

ArunA Biomedical Announces Co-development of Fully Validated Induced Pluripotent Stem Cell Kit

March 31, 2009 (Athens, GA) ArunA Biomedical, Inc., a leader in human embryonic stem cell derived products, announced today that it has co-developed a validated kit to produce induced pluripotent stem cells with Open Biosystems now part of Thermo Fisher.

In the spirit of collaboration ArunA Biomedical and Open Biosystems will launch the complete and fully validated induced pluripotent stem cell (iPS) kits containing all the tools and reagents necessary to generate patient and disease specific cell lines for use in research applications in early April. The innovative viPS™ product offerings will include two kit formats and additional supplemental kits designed exclusively by the companies.

ArunA co-founder and CSO, Steven Stice said, “These kits are consistent with the scientific vision of our company. They exemplify ArunA’s commitment to making stem cell research easier thereby enabling investigators the opportunity to make faster advances in the stem cell field. Induced pluripotent cells generated from these kits can help find cures for many genetic disorders ranging from certain types of Alzheimer’s to Huntington’s disease. ”

The products will be marketed by Open Biosystems, now part of Thermo Fisher.

More About Aruna

Iconic Therapeutics raises $2.5M from local angels and East Coast VC

January 7, 2009 (Atlanta, GA) Iconic Therapeutics Inc., a biotech company developing a drug to treat wet macular degeneration, has raised $2.5 million from New Haven, Conn-based Elm Street Ventures, the ATDC Seed Capital Fund and undisclosed local angel investors.

The raise is part of $4.2 million Series C round, which Iconic expects to complete in the next 60 days, president Kirk Dornbush said. Iconic has raised $11.9 million since its inception in 2003, mostly from angels, Dornbush said.

Wet macular degeneration is the leading form of blindness in adults over 50, with more than one million new cases are diagnosed annually.

Vision loss is due to the growth of abnormal blood vessels called choroidal neovascularization (CNV) in the choriocapillaries. These CNV puncture the Bruch's membrane and leak a fluid which obscures vision, much like the vision of a snorkeler would be impaired if water filled his mask, Dornbush said. The bleeding, leaking, and scarring from these blood vessels eventually cause irreversible damage to the photoreceptors and rapid vision loss if left untreated.

Iconic, which licensed the rights to hI-con1, from Yale University in 2003, plans to conduct a 50-patient clinical trial to show that the compound is safe in humans. Iconic plans to start clinical trials in May, but must first get FDA clearance.

hI-con1 binds a protein, called tissue factor, found on the surface of the vascular endothelial cells lining the CNV. Once bound to target CNV cells, hI-con1™ triggers the immune system to selectively destroy those cells.

hI-con1 “is one of the few agents in the area of treating wet MD is specifically designed to trigger scarless regression of CNV,” Dornbush said. “In experiments at the University of Louisville in their porcine wet [macular degeneration] model, hI-con1 has consistently triggered significant regression of these pathological blood vessels.”

Iconic, which has no product on the market, raised $3.1 million in 2008 — a year in which the biotech industry saw a 56 percent drop in net capital, Dornbush said.

“Considering how much we raised and when we raised it, which is in the midst of the worst financial crisis in 70 years and the most difficult environment for biotech companies ever,” Dornbush said, “it speaks volumes about the excitement for the technology.”

More About Iconic Therapeutics

Abeome Announces First-Class Scientific Advisory Board to Support its Research Activities

September 9, 2008 (Athens, GA) Abeome Corporation, a Georgia-based biotech company, today announced the formation of its Scientific Advisory Board (SAB) to collaborate on the development of Abeome’s ovarian cancer project and to select and guide future therapeutic and diagnostic projects for the company.

The SAB will be led by scientific founder Richard Meagher, PhD, Chief Scientific Officer for Abeome, Distinguished Research Professor at the University of Georgia, and inventor of Abeome’s patented monoclonal antibody technology. The SAB will consist of:

Christine Debouck, PhD, President of Ardennes Biosciences LLC and formerly Senior VP in R&D at GlaxoSmithKline, is renowned for her expertise in target validation, disease knowledge and compound characterizations as well as for her broad scientific applications of biotechnology, genomics and biomarker discovery in pre-clinical and clinical development, and biomarker evaluation with an emphasis in oncology and infectious diseases. Dr. Debouck brings 24 years of experience in directing creative science in diverse areas of research.

Jeff Boyd, PhD, Chief Scientific Officer and Sr. VP at Fox Chase Cancer Center in Philadelphia, has an international reputation as one of the leading scientists in the study of molecular genetics of women’s cancers. Dr. Boyd was named Distinguished Cancer Scholar by the Georgia Cancer Coalition. His long-term research focus has studied molecular genetics of ovarian cancer with emphasis on hereditary predisposition.

Linda Matsuuchi, PhD, Associate Director of the Life Sciences Institute at the University of British Columbia, has a distinguished research career focused on intracellular trafficking and cell signaling of specific membrane receptors on the cell surface of B lymphocytes, the source of antibody production.

“We are pleased to assemble such an incredibly talented team of scientists to serve on our SAB and to participate in target validation on our ovarian cancer therapeutic project. Their active participation provides Abeome with valuable expertise in pre-clinical and clinical trials, unparalleled knowledge of ovarian cancer pathology, and years of immunology experience specific to monoclonal antibody development,” states Abeome CEO, Mike Wanner.

“The company will deploy its monoclonal antibody technology to rapidly develop a pipeline of therapeutic candidates in a number of cancer areas and will benefit by these individual’s commitment to our mission. They join an already outstanding group of Abeome scientists, biotech-oriented Board of Directors, and scientific founder, Dr. Richard Meagher to form a team of world-class scientists to insure Abeome’s future success.”

More About Abeome

ICON Interventional Systems, Inc. Recognized by the Technology Association of Georgia as one of the TOP 40 Most Innovative Technology Companies in Georgia

February 28, 2008 (Atlanta, GA) With nearly 150 companies applying for consideration by the Technology Association of Georgia (TAG) at the Georgia Technology Summit: Innovation In Transformation heldat the Cobb Galleria Centre ICON was selected.

"This was another solid year for the Top 40, with the next generation of Georgia innovators poised to further expand the State's reputation for being a technology hotbed," said Tino Mantella, president of TAG.

The TAG Top 40 are selected based on a number of criteria, includig: degree of innovation, focusing on whether the technology is disruptive or cutting-edge; scope and financial impact of innovation; likelihood of success; and promotion of Georgia's innovative efforts nationally and internationally. "The Top 40 has become more and more competitive every year," said Dennis Zakas, a partner with McKenna Long & Aldridge and chairperson of the Top 40 Selection Committee.

More About Icon Interventional


© Georgia Venture Partners, Inc.